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Why a brain tumor found on a preventive scan does not make full-body MRI a routine test

Medical groups and UCSF researchers warn that routine full-body MRI scans for asymptomatic adults may cause more harm than benefit.

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MRI scanner in a clinical room with a patient table extending from the bore.

REDWOOD CITY, Calif., July 21 (San Francisco News Online) — A recent case reported by Fox News, in which a preventive scan found a brain tumor, has renewed attention on full-body MRI. But for most healthy adults in San Francisco and beyond, the key question is not whether an MRI can ever find something serious. It can. The question is whether scanning the whole body early, before symptoms, improves health enough to outweigh the downsides.

The Food and Drug Administration says it knows of no scientific evidence showing that whole-body scanning of people without symptoms provides more benefit than harm. The American College of Radiology says there is not enough evidence to recommend total-body screening for people with no symptoms, no risk factors and no family history suggesting disease. The American Academy of Family Physicians and the American College of Preventive Medicine also advise against using whole-body scans to look for early tumors in people without symptoms.

What a full-body MRI is

A full-body MRI uses magnetic fields and radio waves to make images of the body. It does not use ionizing radiation, unlike a CT scan. That makes the test appealing to some people who want a screening option without radiation exposure.

Some companies market whole-body MRI as a way to find hidden disease early. Prenuvo, for example, says its scan can detect more than 500 conditions, including early-stage tumors. But medical groups say a marketing claim is not the same thing as proof that a scan helps people live longer or better.

Why doctors are cautious

The concern is not only what a scan finds. It is also what it starts.

The American Cancer Society says the main risk comes from downstream effects: a scan may show a spot or shadow that turns out to be harmless, but still leads to more tests, repeat imaging, biopsies or even surgery. The society also warns about false reassurance, when a scan misses a problem and a person wrongly feels protected. It says insurance companies rarely pay for full-body MRI because it is not part of standard medical care.

UCSF radiology researcher Dr. Rebecca Smith-Bindman told CBS San Francisco that there is ‘not a stitch of evidence’ that the scan helps people live longer or better. She also warned of false positives and unnecessary follow-up care.

A JAMA editorial by Matthew Davenport of the University of Michigan and Dr. Scott Reeder said no major medical group recommends whole-body MRI for the general population because the benefits remain unproven. Davenport said the harms can come from invasive testing, surgery or follow-up of findings whose benefit is unclear.

What one success story does – and does not – prove

A case where a scan finds a tumor before symptoms can sound persuasive. But one case does not show what happens for most people. The U.S. Preventive Services Task Force, for example, gives pancreatic cancer screening in asymptomatic adults who are not known to be at high risk a D rating, meaning the harms outweigh the benefits.

That is why the broader medical message remains cautious. Full-body MRI may sometimes find disease early, but major groups say the evidence has not shown that routine screening of healthy people improves outcomes enough to justify the possible harm, stress and expense.

In San Francisco, that debate is especially visible because UCSF researchers have been among the most outspoken critics of routine whole-body screening. For now, the official guidance is consistent: full-body MRI is not recommended as a routine screening test for people without symptoms or clear risk factors.

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